Stec- Postdoctoral Fellowship Ad

Postdoctoral Position in the Laboratory of Dr. David E. Stec, Professor, Department of Physiology & Biophysics, University of Mississippi Medical Center, Jackson, Mississippi

The Department of Physiology & Biophysics at the University of Mississippi Medical Center in Jackson, Mississippi invites applications for a Postdoctoral Fellowship in the role of bilirubin and biliverdin reductase in nonalcoholic fatty liver disease (NAFLD) in the NIH funded laboratory of David E.Stec, Ph.D. The Department of Physiology & Biophysics is an internationally recognized leader in Cardiovascular Physiology and Metabolism and is located in a modern, fully equipped state-of-the art research facility in the Arthur C. Guyton Research Building on the Campus of the University of Mississippi Medical Center in Jackson, MS. The Department of Physiology & Biophysics provides an excellent environment for postdoctoral training. Postdoctoral researchers in the Department routinely win awards from such organizations as the American Physiological Society and the American Heart Association.

The overall goal of the research program is to determine the mechanism by which bilirubin and biliverdin reductase protect against NAFLD and to develop novel therapeutics to treat NAFLD which is an emerging pathology associated with obesity. Research projects include: identification of the mechanisms by which bilirubin increases fatty acid oxidation in the liver; discovery of the novel mechanisms to increase bilirubin in individuals with low serum bilirubin levels; investigation of the relationship between bilirubin and peroxisome proliferator-activated receptor-α (PPARα) utilizing hepatocyte-specific PPARα knockout mice; investigating the role of hepatic biliverdin reductase in the regulation of NAFLD utilizing hepatocyte-specific BVRA knockout mice. The position offers the opportunity to gain technical experience in measurement of whole body metabolism, hyperinsulinemic-euglycemic clamp energy balance and body composition assessment, and molecular biological laboratory techniques. Candidates should have a Ph.D., M.D., or D.V.M and experience in animal studies with demonstrated analytical skills. Experience with animal surgery and molecular biology techniques is preferable. Excellent written and verbal communication skills are required. This position has a minimum of a two year term and salary is commensurate with experience based on current NIH guidelines. Equal opportunity employer, M/F/D/V.

Send letter of interest, CV, and names of 3 references to David E. Stec, Ph.D., Professor of Physiology & Biophysics, University of Mississippi Medical Center, 2500 North State Street, Jackson, Mississippi 39216. Email:dstec@umc.edu